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Approval of the study was obtained by the institutional review board committee and governmental institution (Ministry of Health approval no. In 2009, a second generation, battery-operated LUCAS 2 was launched globally. mphillips@pedidevices.com (214) 497-2533. If ROSC was not achieved, CPR was resumed and continued for 1 minute before a subsequent defibrillation with an escalating energy strategy (300‐360‐j). The hypothesis on whether mechanical CC would improve systemic perfusion compared with manual CC was tested in a preclinical porcine model of out‐of‐hospital cardiac arrest. Mechanical CC accounted also for a better CC quality, with a lesser rescuer's physical effort requirements, compared with manual CC.The study may have a potential impact on the rescuers’ decision on whether stay on the scene or transport the cardiac arrest patient to the hospital with an ongoing mechanical CPR.Clinical Department, Stryker/Jolife AB, Lund, SwedenThe study provides evidence to the current knowledge gap on mechanical CPR during transport as claimed in the 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations.The suggestion to use a mechanical compressor to deliver sustained high‐quality chest compression (CC) in a moving ambulance has been supported only by data on the quality of cardiopulmonary resuscitation (CPR) metrics.Authors thank Dr Fredrik Arnwald Clinical Department, Stryker/Jolife AB, Lund, Sweden for having supported the proposal.Data are reported in mean±SEM, except for hs‐cTnT and NSE that are expressed as median [interquartile range]. hs‐cTnT indicates highsensitivity cardiac troponin T; NSE, neuron‐specific enolase.This model adds evidence in favor of the use of mechanical devices to provide ongoing high‐quality CC and tissue perfusion during ambulance transport.Data are reported as mean±SEM or median [interquartile range]. Return of spontaneous circulation (ROSC) was defined as the presence of sinus rhythm with a mean arterial pressure of >60 mmHg.
In the end of the 90s, the development of the LUCAS device was started.In 2003, the first pneumatic LUCAS 1 devices were used clinically in ambulances in Sweden. Given the need for pediatric medical and surgical devices and the challenges to pediatric device development, off-label use is a necessary and appropriate part of care. He approached Professor Stig Steen of Lund University Hospital, Sweden, with an idea to overcome the limitations of manual CPR by making an automated chest compressor. At the end of the 72‐hour post resuscitation observation, animals were reanesthetized for echocardiographic examination and blood sample withdrawn. Professional Services. 979/2017‐PR). The secondary aim was the comparison of CC quality between the 2 CPR strategies during transport. Animals were then returned in the operating room, where they were monitored for an additional 3 hours, under anesthesia.
Catheters were then removed, wounds were repaired, and the animals were extubated and returned to their cages. Pediatric medical devices treat or diagnose diseases and conditions from birth through age 21. The same resuscitation protocol was continued until successful resuscitation or for a maximum of 5 additional minutes.Beside the driver and a copilot, the ambulance cabin crew consisted of 2 certified professional rescuers who alternated each other in performing manual CC every 2 minutes, and 1 operator responsible for drug administration and arterial blood sampling.